Easy Pepperoni Pizza Bake with Golden Biscuit Crust Tips, FAQ & printable recipe

Tips for success

To elevate the flavor of this simple bake, consider sprinkling a tablespoon of Italian seasoning or dried oregano over the cheese before baking.

A dusting of freshly grated Parmesan cheese right as the casserole comes out of the oven adds a wonderful salty, savory depth. For a touch of freshness, garnish the baked dish with thinly sliced fresh basil leaves just before serving.

If you prefer a crispier crust, you can pre-bake the biscuit pieces alone for about five minutes before adding the sauce, cheese, and toppings.

This initial bake helps set the dough, ensuring it stays light and airy even under the weight of the heavy sauce and cheese. Always ensure your mozzarella is low-moisture to avoid excess water pooling on top.

Variations

• Supreme Pizza Bake: Add diced green bell peppers, sliced black olives, and cooked Italian sausage along with the pepperoni before baking.
• Three-Cheese Pizza Bake: Combine the mozzarella with shredded provolone and Monterey Jack cheese for an extra gooey, multi-dimensional cheese blend.

Storage and make-ahead

Fridge

Store leftovers in an airtight container in the refrigerator for up to 3 days.

Freezer

Freeze baked portions wrapped tightly in foil and plastic wrap for up to 2 months. Thaw in the fridge overnight before reheating.

Reheat

Reheat individual slices in a 350°F (175°C) oven or toaster oven for 10 minutes, or microwave on high for 1 to 2 minutes until hot.

Store any leftover pizza bake in an airtight container in the refrigerator for up to three days. To preserve the texture of the crust, avoid stacking the slices directly on top of each other.

If storing in the baking dish, cover it tightly with plastic wrap or aluminum foil once the casserole has cooled completely to room temperature.

This casserole can be assembled up to four hours in advance. Keep the assembled, unbaked dish covered with plastic wrap in the refrigerator. When ready to eat, bake according to the recipe instructions, adding about five extra minutes to the baking time to account for the cold dish and ingredients straight from the fridge.

Serving ideas

Serve this comforting pizza bake warm, sliced into generous squares using a sharp knife or a metal spatula to lift each portion cleanly. The dramatic cheese pull is best enjoyed when the dish is fresh and hot. Pair each serving with a crisp, green side salad tossed in a simple red wine vinaigilege to balance the rich, cheesy flavors.

This dish also pairs wonderfully with warm garlic bread or breadsticks for dipping into extra warm pizza sauce on the side.

For a fun family-style presentation, place the wooden board with the hot glass dish directly in the center of the table, allowing everyone to scoop out their own portions while the cheese is still beautifully melted and stringy.

Frequently asked questions

Recipe card

Easy Pepperoni Pizza Bake with Golden Biscuit Crust

Prep 15 minCook 25 minRest 5 minTotal 45 minServes 6

Ingredients

• 16 oz refrigerated biscuit dough, cut into bite-sized pieces
• 1 1/2 cups pizza sauce
• 2 cups shredded mozzarella cheese
• 3 oz sliced pepperoni

Instructions

1. Preheat the oven to 375°F (190°C). Lightly grease a 9x13-inch glass baking dish with nonstick cooking spray or olive oil to ensure the pizza bake releases easily after baking.
2. Open the can of refrigerated biscuit dough. Cut each individual biscuit into eight equal, bite-sized pieces using a sharp chef's knife or kitchen shears, keeping the pieces separated.
3. Place the biscuit pieces into a large mixing bowl. Pour the pizza sauce over the dough and gently toss with a spatula until every piece is completely and evenly coated with sauce.
4. Transfer the saucy biscuit pieces into the prepared glass baking dish, spreading them into an even layer. Sprinkle the shredded mozzarella cheese uniformly over the top, then arrange the pepperoni slices in a single layer over the cheese.
5. Bake at 375°F (190°C) for 22 to 25 minutes. The cheese should be bubbling and golden-brown, and the biscuits cooked through. Remove from the oven and let rest for 5 minutes before serving.

Contains: gluten, milk

Estimated nutrition per serving

Calories

420

Protein

18 g

Carbohydrates

34 g

Fat

24 g

Fiber

1.5 g

Sugar

4 g

Sodium

1150 mg

Automatic estimate from the ingredient list, not laboratory-verified.