Creamy Garlic Butter Chicken Penne Casserole Tips, FAQ & printable recipe

Tips for success

If you find the sauce is becoming too thick while simmering, add a small splash of pasta cooking water to loosen it before combining with the penne. This starchy liquid helps create a glossy finish that makes the dish look even more appetizing.

Additionally, always grate your own mozzarella from a block if possible. Pre-shredded cheese is often coated in anti-caking agents that prevent it from melting into that smooth, gooey texture that is essential for a great pasta bake.

For those who enjoy a bit of texture, consider adding a handful of toasted breadcrumbs mixed with a little melted butter over the top of the cheese during the last few minutes of baking. This provides an extra layer of crunch that contrasts wonderfully with the creamy pasta.

If you prefer a more vibrant look, a light sprinkle of fresh chopped parsley after pulling the dish from the oven adds a pop of color and a fresh, herbal note that cuts through the richness of the cream.

Variations

• Spinach and Mushroom: Add two cups of fresh baby spinach and a cup of sliced sautéed mushrooms to the sauce during the final assembly. This adds earthy flavors and a boost of color to the dish.
• Spicy Cajun Style: Stir in one tablespoon of Cajun seasoning to the chicken while it sears. This adds a bold, spicy kick that pairs perfectly with the creamy garlic butter sauce.

Storage and make-ahead

Fridge

Store in an airtight container for up to 3 days.

Freezer

Freeze for up to 1 month in a freezer-safe container.

Reheat

Reheat in a preheated oven at 350°F (175°C) until warmed through, or use a microwave for smaller portions.

Store any leftovers in an airtight container to maintain freshness. Ensure the casserole has cooled to room temperature, but do not leave it out for more than two hours to ensure food safety. Properly stored, the dish will stay fresh in the refrigerator for up to three days.

When ready to eat again, keep in mind that the pasta will continue to absorb some of the sauce, so you might want to add a tiny splash of water or cream when reheating to restore the original creamy texture.

This dish is excellent for make-ahead meals. You can assemble the entire casserole, cover it tightly, and keep it in the refrigerator for up to 24 hours before baking. When ready to cook, simply remove it from the fridge and let it sit on the counter for about 20 minutes to take the chill off before placing it in the oven. You may need to add an extra 5 to 10 minutes to the total baking time to ensure it is heated through completely.

Serving ideas

Serve this dish directly from the baking dish for a rustic, family-style presentation. Provide a large serving spoon and ensure everyone gets a portion that includes plenty of the cheesy, crusty top. It pairs wonderfully with a side of steamed green vegetables or a crisp, light garden salad to balance the richness of the creamy pasta. A simple side of toasted garlic bread can also be a nice addition for those who want to soak up any remaining sauce on their plates.

When plating, try to scoop from the center outward to preserve the beautiful cheese pull. Since this is a very hearty meal, smaller portions are often sufficient, especially when accompanied by sides. Ensure that each serving gets a good mix of the chicken and the saucy pasta.

If you have guests, consider setting out some extra grated parmesan or red pepper flakes on the table so everyone can customize their own portion to their personal taste preferences before diving into the meal.

Frequently asked questions

Recipe card

Creamy Garlic Butter Chicken Penne Casserole

Prep 15 minCook 30 minRest 5 minTotal 50 minServes 6

Ingredients

• 1 lb penne pasta
• 1.5 lb chicken breast, cubed
• 4 tbsp butter
• 3 cloves garlic, minced
• 1 cup creamy sauce base
• 2 cups shredded mozzarella cheese

Instructions

1. Bring a large pot of salted water to a boil and cook the penne according to package instructions until al dente. Drain well and set aside. Preheat the oven to 375°F (190°C).
2. In a skillet, sear the cubed chicken breast over medium-high heat. Add butter and minced garlic, sautéing until fragrant. Pour in the creamy sauce base and simmer until slightly thickened. Ensure the chicken reaches an internal temperature of 165°F (74°C).
3. Combine the cooked pasta and the creamy chicken sauce in a 9x13 inch baking dish. Top evenly with the shredded mozzarella cheese. Bake for 15 minutes or until the cheese is melted and bubbling.

Contains: gluten, milk

Estimated nutrition per serving

Calories

650

Protein

35 g

Carbohydrates

55 g

Fat

32 g

Automatic estimate from the ingredient list, not laboratory-verified.